منابع مشابه
Alcohol relaxes the stiff heart.
Dynamic obstruction of the left ventricular outflow tract (LVOT) has been related to symptoms of dyspnoea, angina, and syncope in patients with hypertrophic obstructive cardiomyopathy (HOCM). In 1995, Sigwart introduced an ingenious catheter-based technique for septal reduction by infusing a small amount of absolute ethanol into the first or second septal arteries supplying the obstructing sept...
متن کاملHow the heart relaxes
Normal functioning of the heart is dependent on its ability both to contract and relax. Heart contraction is a complex process that is initiated by an increase in intracellular calcium, which results in myosin binding to actin and myosin movement of the actin filament. Relaxation is reliant on removal of calcium from the contractile filaments, which in turn is dependent on the availability of A...
متن کاملAlcohol and the heart.
Acute effects of alcohol on the heart manifest themselves haemodynamically as an increase of the left-ventricular pressure with decrease of the stroke volume, when the left-ventricular ejection fraction is reduced, on the basis of a disturbance of the systolic pumping function. The most important acute alcohol-conditioned metabolic disturbances of the myocardium are described. The disturbance o...
متن کاملEthyl alcohol and the heart.
Since a significant fraction of the population are heavy consumers of ethanol, and recent postmortem studies suggest that most alcoholics have some degree of cardiac abnormality, elucidation of the basis for alcoholic cardiomyopathy is of some importance. Intoxicating amounts of ethanol depress ventricular function acutely and effect leakage of myocardial cell components. On the basis of studie...
متن کاملThe Stiff Left Atrium Is to Atrial Fibrillation as the Stiff Left Ventricle Is to Diastolic Heart Failure.
Atrial fibrillation (AF) is the most common cardiovascular disorder present in as many as 9% of subjects aged ≥65 years and costing the United States >26 billion dollars a year. It causes significant morbidity and mortality with 750 000 hospitalizations each year and contributing to an estimated 130 000 deaths each year. Risk factors for AF such as obesity, diabetes mellitus, coronary artery di...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2006
ISSN: 0195-668X,1522-9645
DOI: 10.1093/eurheartj/ehl127